Fosbretabulin (tromethamine)

• UNSPSC Description:

  Fosbretabulin (tromethamine), also known as combretastatin A4 phosphate (CA4P), is a vascular disrupting agent evaluated for its efficacy against anaplastic thyroid carcinoma (ATC). It targets tumor neovasculature, causing acute and reversible reductions in tumor blood flow and central necrosis[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/fosbretabulin-tromethamine.html

• Smiles:

  OCC(CO)(N)CO.O=P(O)(O)OC1=C(C=CC(/C=C\C2=CC(OC)=C(C(OC)=C2)OC)=C1)OC

• Molecular Weight:

  517.46

• References & Citations:

  [1]Fosbretabulin tromethamine in the treatment of thyroid cancer

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 3

• CAS Number:

  404886-32-4