Products for Research Use Only
RegisterLogin

Fosbretabulin

CAT: 0804-HY-14815Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14815Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Fosbretabulin (Combretastatin A4 phosphate) is a vascular disruptor with antitumor activity against atypical thyroid carcinoma (ATC) cell lines and xenografts. Fosbretabulin inhibits tumor growth by inhibiting microtubule polymerization, inducing apoptosis, and suppressing angiogenesis in tumors[1].
CAS Number
222030-63-9
Product Name Alternative
Combretastatin A4 phosphate
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fosbretabulin.html
Smiles
O=P(O)(O)OC1=C(C=CC(/C=C\C2=CC(OC)=C(C(OC)=C2)OC)=C1)OC
Molecular Formula
C18H21O8P
Molecular Weight
396.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Mooney, et al. "A phase II trial of fosbretabulin in advanced anaplastic thyroid carcinoma and correlation of baseline serum-soluble intracellular adhesion molecule-1 with outcome." Thyroid 19.3 (2009) : 233-240.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

Alternative Products

CatalogName
T210328-01Fosbretabulin tromethamine
GTR19172008-01Fosbretabulin Disodium
T31857-01Fosbretabulin [free base]
GTR19154679-01Fosbretabulin disodium (CA4P)
A13081-100Fosbretabulin disodium (CA4P) 100mg
A13081-1Fosbretabulin disodium (CA4P) 1mg
A13081-50Fosbretabulin disodium (CA4P) 50mg
A13081-5Fosbretabulin disodium (CA4P) 5mg
A13081-25Fosbretabulin disodium (CA4P) 25mg
A13081-10Fosbretabulin disodium (CA4P) 10mg

Popular Products