Products for Research Use Only
RegisterLogin

Lobaplatin

CAT: 0804-HY-105930-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-105930-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Lobaplatin (D-19466) is a diastereometric mixture of platinum (II) complexe. Lobaplatin arrests cell cycle at G1 and G2/M phase. Lobaplatin induces apoptosis by increasing expressions of caspase and Bax, decreasing expression of Bcl-2. Lobaplatin can be used for research of cancer[1][2][3].
CAS Number
135558-11-1
Product Name Alternative
D-19466
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Bcl-2 Family; Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lobaplatin.html
Purity
98.0
Solubility
DMSO : 4.55 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1[O-][Pt+2]2([O-]C1=O)[NH2]CC(CC3)C3C[NH2]2
Molecular Formula
C9H18N2O3Pt
Molecular Weight
397.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Du L, et, al. Antitumor activity of Lobaplatin against esophageal squamous cell carcinoma through caspase-dependent apoptosis and increasing the Bax/Bcl-2 ratio. Biomed Pharmacother. 2017 Nov;95:447-452.|[2]Wu Q, et, al. Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells. J Hematol Oncol. 2010 Oct 31;3:43.|[3]McKeage MJ. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10 (1) :119-28.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 4

Alternative Products

CatalogName
BA2842-25Lobaplatin
A19203-5Lobaplatin 5mg
AR-L07580-01Lobaplatin (trans)
A19203-1Lobaplatin 1mg
A19203-50Lobaplatin 50mg
A19203-25Lobaplatin 25mg
A19203-10Lobaplatin 10mg
AR-L07581-01R-Lobaplatin (trans)
AR-L07588-01Lobaplatin Impurity 9
RM-L150104-01Lobaplatin Impurity 4

Popular Products