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Human CD161 Protein, hFc Tag

CAT: 0793-32-18330-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0793-32-18330-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Description :Recombinant human CD161 Protein with N-terminal human Fc tagBackground : Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. Molecular Characterization: mass of 44.6 kDa after removal of the signal peptide. The apparent molecular mass of hFc-CD161 is approximately 55-70 kDa due to glycosylation.Tag :N-Human Fc Tag
Product Name Alternative
NKR; KLRB1; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A
UniProt
Q12918
Host
HEK293
Target Antigen
CD161
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
Storage Conditions
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

UniProtKB · Q12918

Killer cell lectin-like receptor subfamily B member 1

KLRB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q12918
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KLRB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q24K24
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Disulfide bondGlycoprotein

Ligand

Lectin

Cellular component

Membrane

Molecular function

Receptor

Domain

Signal-anchorTransmembraneTransmembrane helix

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Alternative Products

CatalogName
PROTQ12918-250ugHuman CD161 Recombinant Protein
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