Spermine (N3BBB)

• Description :

  Spermine (N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• UNSPSC :

  12352211

• Target :

  ADC Linker

• Type :

  Reference compound

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/spermine-n3bbb.html

• Purity :

  98.04

• Solubility :

  DMSO : 250 mg/mL (ultrasonic)

• Smiles :

  [N-]=[N+]=NCCCN(CCCCN(CCCNC(OC(C)(C)C)=O)C(OC(C)(C)C)=O)C(OC(C)(C)C)=O

• Molecular Formula :

  C25H48N6O6

• Molecular Weight :

  528.69

• References & Citations :

  [1]Roeland Vanhoutte, et al. Clickable Polyamine Derivatives as Chemical Probes for the Polyamine Transport System. Chembiochem. 2018 May 4;19 (9) :907-911.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1190203-80-5]