RegisterLogin

BACE1 Human

CAT: 0793-32-6677-10Size: 10 µgDry Ice: NoHazardous: No
CAT#:0793-32-6677-10Size:10 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Source: Sf9, Baculovirus cells.Sterile Filtered colorless solution.Beta-secretase 1 or BACE1 or beta-site amyloid precursor protein cleaving enzyme 1, is a protein that is encoded by the BACE1 gene in humans. Expression of BACE1 is seen primarily in neurons as it is crucial for the creation of myelin sheats in the peripheric nervous system. Beta-secretase 1 is a proteas that is located in the cell membrane (transmembrane) . The enzyme consists of 2 active sites (aspartate residues) in the extracellular domain that can act as a dimer.BACE1 Human produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 442 amino acids (22-457 a.a.) and having a molecular mass of 49.2kDa. BACE1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Product Name Alternative
Beta-Secretase, Membrane-Associated Aspartic Protease, Beta-Site APP Cleaving Enzyme, Beta-Site APP-Cleaving Enzyme, Aspartyl Protease, EC 3.4.23.46, Memapsin-2, Asp, BACE, ASP2, Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme, Beta-Site Amyloid Precursor Protein Cleaving Enzyme, Tran
Applications
Functional Assay
Purification
Greater than 90.0% as determined by SDS-PAGE.
Components
BACE1 protein solution containing Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.
Applications Notes
Specific activity is > 5 pmol/min/ug in which one unit will convert 1.0 pmole of Mca-SEVNLDAEFRK (Dnp) RR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25C.
Amino Acids
TQHGIRLPLR SGLGGAPLGL RLPRETDEEP EEPGRRGSFV EMVDNLRGKS GQGYYVEMTV GSPPQTLNIL VDTGSSNFAV GAAPHPFLHR YYQRQLSSTY RDLRKGVYVP YTQGKWEGEL GTDLVSIPHG PNVTVRANIA AITESDKFFI NGSNWEGILG LAYAEIARPD DSLEPFFDSL VKQTHVPNLF SLQLCGAGFP LNQSEVLASV GGSMIIGGID HSLYTGSLWY TPIRREWYYE VIIVRVEING QDLKMDCKEY NYDKSIVDSG TTNLRLPKKV FEAAVKSIKA ASSTEKFPDG FWLGEQLVCW QAGTTPWNIF PVISLYLMGE VTNQSFRITI LPQQYLRPVE DVATSQDDCY KFAISQSSTG TVMGAVIMEG FYVVFDRARK RIGFAVSACH VHDEFRTAAV EGPFVTLDME DCGYNIPQTD ESTLMTHHHH HH.

Related Products

CatalogName
32-17573-50Human BACE1 Protein, His Tag
32-17573-10Human BACE1 Protein, His Tag
32-9907-500Recombinant Human BACH1 (C-His)
32-9907-50Recombinant Human BACH1 (C-His)
32-190044-50IL-6 (human) :Fc (human) (Recombinant)
32-6527-25PLGF3 Human
32-6547-10RBP3 Human
32-6549-50SAA Human
32-6569-10TNFRSF8 Human
32-6569-2TNFRSF8 Human

Alternative Products

CatalogName
BIO0442SM-1mgAnti-human BACE1 (Genentech Anti-BACE1 Biosimilar)
MBS554257-01Human BACE1 Recombinant
MBS8226367-01BACE1 siRNA (Human)
12970051BACE1 Adenovirus (Human)
HY-P72840-01BACE1, Human (HEK293)
B2016790Human BACE1 (recombinant)
RPF11065-01Recombinant Human BACE1
E55A13065Human BACE1 Nanobody
12971051BACE1-AS Adenovirus (Human)
abx900582-01Human bACE1 siRNA

Popular Products