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SRANKL (158-316) Mouse

CAT: 0793-32-6541-2Size: 2 µgDry Ice: NoHazardous: No
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CAT#:0793-32-6541-2Size:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source: Escherichia Coli. Sterile Filtered colorless solution. RANKL binds to tnfrsf11b/opg and to tnfrsf11a/rank. Osteoclast differentiation and activation factor. augments the ability of dendritic cells to stimulate naive t-cell proliferation. May be an important regulator of interactions between t-cells and dendritic cells and may play a role in the regulation of the t-cell-dependent immune response. sRANKL may also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. sRANKL Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 160 amino acids (158-316 a.a.) and having a molecular mass of 17.9kDa. sRANKL is purified by proprietary chromatographic techniques.
Product Name Alternative
Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sR
Applications
Functional Assay
Purification
Greater than 90% as determined by SDS-PAGE.
Components
SRANKL protein solution (1mg/mL) containing Tris-Hcl buffer pH-8.5 and 0.1M NaCl.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Avoid multiple freeze-thaw cycles.
Applications Notes
The ED50, as measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells, is less than 2ng/ml.
Amino Acids
MKPEAQPFAH LTINAASIPS GSHKVTLSSW YHDRGWAKIS NMTLSNGKLR VNQDGFYYLY ANICFRHHET SGSVPTDYLQ LMVYVVKTSI KIPSSHNLMK GGSTKNWSGN SEFHFYSINV GGFFKLRAGE EISIQVSNPS LLDPDQDATY FGAFKVQDID

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Alternative Products

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OM301433-01SRANKL (158-316) Mouse
GTR18984671-01Mouse sRANKL (158-316) Protein
PROTQ3TWY5sRANKL (158-316) Soluble RANK Ligand (158-316 a.a) Mouse Recombinant Protein
MBS146730-01Recombinant Mouse Soluble RANK Ligand (158-316 a.a)
rAP-2458Soluble RANK Ligand (158-316 a.a) Mouse Recombinant
OM301429-01SRANKL Mouse
TMPY-07194-01RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 158-316, His)
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