IL-2 Canine

CAT: 0793-32-6419-100Size: 100 µgDry Ice: NoHazardous: No
CAT#:0793-32-6419-100Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.IL2 is a secreted cytokine that is essential for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 and interleukin 7. The expression of IL2in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the exact expression of a single gene.Interleukin-2 Canine Recombinant produced in E. coli is a non-glycosylated monomer chain containing 136 amino acids and having a molecular mass of 15.6kDa. IL-2 is purified by proprietary chromatographic techniques.
Product Name Alternative
Interleukin-2, IL-2, T-cell growth factor, TCGF.
Applications
Functional Assay
Purification
Greater than 95.0% as determined by SDS-PAGE.
Components
The protein was lyophilized from a sterile (0.2μm) filtered solution containing 20 mM sodium bicarbonate, pH 8.5.It is recommended to reconstitute the lyophilized IL-2 in Sterile 10 mM sodium bicarbonate, pH 8.5 at 0.1 mg/mL, which can then be further diluted to other aqueous solutions.
Storage Conditions
Lyophilized IL-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-2 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Applications Notes
The ED50, as determined by CTLL-2 cell proliferation is = 2.0 x 10^5 units/mg.
Amino Acids
MAPITSSSTK ETEQQMEQLL LDLQLLLNGV NNYENPQLSR MLTFKFYTPK KATEFTHLQC LAEELKNLEE VLGLPQSKNV HLTDTKELIS NMNVTLLKLK GSETSYNCEY DDETATITEF LNKWITFSQS IFSTLT.

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