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Recombinant Human Matrix Gla Protein

CAT: 0793-32-4207-20Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0793-32-4207-20Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : E.coli. MGP Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 98 amino acids (20-96) and having a molecular mass of 11.8 kDa.The MGP is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. MGP is vital for the regulation of calcification in the extracellular matrix, particularly in cartilage and arteries. The K-dependent vitamin MGP has five to six residues of Gla, a Ca2+ binding amino acid crucial for vitamin K-dependent gamma carboxylase for its formation. MGP is formed by COOH-terminal processing by carboxypeptidase B-like enzymatic activity and localized in the human bone.
Product Name Alternative
Matrix Gla protein||Cell growth-inhibiting gene 36 protein||MGLAP||NTI.
Purification
Greater than 90% as determined by SDS-PAGE.
Components
The MGP solution (1mg/mL) contains 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.
Amino Acids
MGSSHHHHHH SSGLVPRGSH MYESHESMES YELNPFINRR NANTFISPQQ RWRAKVQERI RERSKPVHEL NREACDDYRL CERYAMVYGY NAAYNRYF