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PSMB3 Recombinant Protein

CAT: 0793-32-2750-20Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0793-32-2750-20Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : Escherichia Coli. PSMB3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 225 amino acids (1-205 a.a.) and having a molecular mass of 25.1kDa.PSMB3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. The proteasome is a multicatalytic proteinase complex with an extremely organized ring-shaped 20S core structure. The core structure consists of 4 rings of 28 non-identical subunits; 2 rings consist of 7 alpha subunits and 2 rings consist of 7 beta subunits. Proteasomes are spread all over the eukaryotic cells in large quantities and cleave peptides in an ATP/ubiquitin-dependent procedure in a non-lysosomal pathway. A vital role of a modified proteasome, the immunoproteasome, is the handling of class I MHC peptides.
Product Name Alternative
Proteasome (prosome||macropain) subunit beta type 3||Proteasome chain 13||HC10-II||Proteasome component C10-II||Proteasome theta chain||EC 3.4.25.1||MGC4147.
Purification
Greater than 90.0% as determined by SDS-PAGE.
Components
PSMB3 protein solution (0.25mg/mL) containing 20mM Tris-HCl buffer (pH8.0), 200mM NaCl, 1mM DTT and 50% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.
Amino Acids
MGSSHHHHHH SSGLVPRGSH MSIMSYNGGA VMAMKGKNCV AIAADRRFGI QAQMVTTDFQ KIFPMGDRLY IGLAGLATDV QTVAQRLKFR LNLYELKEGR QIKPYTLMSM VANLLYEKRF GPYYTEPVIA GLDPKTFKPF ICSLDLIGCP MVTDDFVVSG TCAEQMYGMC ESLWEPNMDP DHLFETISQA MLNAVDRDAV SGMGVIVHII EKDKITTRTL KARMD

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