Products for Research Use Only
RegisterLogin

HMBS Recombinant Protein

CAT: 0793-32-2440-20Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0793-32-2440-20Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Source : Escherichia Coli. HMBS Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 385 amino acids (1-361) and having a molecular mass of 41.9kDa.HMBS is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Porphobilinogen deaminase (HMBS) belongs to the hydroxymethylbilane synthase superfamily. HMBS is a cytoplasmic enzyme found in the heme synthesis pathway. HMBS is the 3rd enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of 4 porphobilinogen molecules into the linear hydroxymethylbilane. HMBS gene mutations cause errors in pyrrole metabolism which in turn lead to the autosomal dominant disease acute intermittent porphyria.
Product Name Alternative
Porphobilinogen deaminase||PBG-D||Hydroxymethylbilane synthase||HMBS||Pre-uroporphyrinogen synthase||HMBS||PBGD||UPS||PORC.
Purification
Greater than 95.0% as determined by SDS-PAGE.
Components
The HMBS solution (1mg/mL) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.
Amino Acids
MGSSHHHHHH SSGLVPRGSH MGSHMSGNGN AAATAEENSP KMRVIRVGTR KSQLARIQTD SVVATLKASY PGLQFEIIAM STTGDKILDT ALSKIGEKSL FTKELEHALE KNEVDLVVHS LKDLPTVLPP GFTIGAICKR ENPHDAVVFH PKFVGKTLET LPEKSVVGTS SLRRAAQLQR KFPHLEFRSI RGNLNTRLRK LDEQQEFSAI ILATAGLQRM GWHNRVGQIL HPEECMYAVG QGALGVEVRA KDQDILDLVG VLHDPETLLR CIAERAFLRH LEGGCSVPVA VHTAMKDGQL YLTGGVWSLD GSDSIQETMQ ATIHVPAQHE DGPEDDPQLV GITARNIPRG PQLAAQNLGI SLANLLLSKG AKNILDVARQ LNDAH.

Related Products

CatalogName
32-7716-50Recombinant Human Porphobilinogen Deaminase/HMBS/PBGD (C-6His)
32-7716-10Recombinant Human Porphobilinogen Deaminase/HMBS/PBGD (C-6His)
32-4513-10Recombinant Protein L
32-3516-20CFL2 Recombinant Protein
32-3507-20CENPP Recombinant Protein
32-3506-10CENPM Recombinant Protein
32-3505-20CENPH Recombinant Protein
32-3502-20CEND1 Recombinant Protein
32-3499-20CEACAM21 Recombinant Protein
32-3494-20CDC123 Recombinant Protein

Alternative Products

CatalogName
OPCD03912-50UGHMBS Recombinant Protein
ARP2459-01Recombinant Human HMBS Protein
TP726950HMBS Human Recombinant Protein
RP141794HMBS Recombinant Protein (Mouse)
PROTP08397-01Human HMBS Recombinant Protein
NBP2-33600PEPHMBS Recombinant Protein Antigen
RP014953HMBS Recombinant Protein (Human)
RP204704HMBS Recombinant Protein (Rat)
TP301362MHMBS (NM_000190) Human Recombinant Protein

Popular Products