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FDFT1 Recombinant Protein

CAT: 0793-32-2321-10Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0793-32-2321-10Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : Escherichia Coli. FDFT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 306 amino acids (1-283 a.a) and having a molecular mass of 35.4 kDa. FDFT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Farnesyl-Diphosphate Farnesyltransferase 1, also known as FDFT1 is a membrane-associated enzyme sited at a branch point in the mevalonate pathway. FDFT1 belongs to the phytoene/squalene synthase family. FDFT1 is the 1st specific enzyme in cholesterol biosynthesis, which catalyzes the dimerization of 2 molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Product Name Alternative
Farnesyl-Diphosphate Farnesyltransferase 1||Squalene Synthase||SQS||SS||FPP:FPP Farnesyltransferase||EC 2.5.1.21||DGPT||ERG9||Presqualene-Di-Diphosphate Synthase||Squalene Synthetase||Farnesyl-Diphosphate||Farnesyltransferase||FDFT1.
Purification
Greater than 85.0% as determined by SDS-PAGE.
Components
FDFT1 protein solution (0.25 mg/mL) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.
Amino Acids
MGSSHHHHHH SSGLVPRGSH MGSMEFVKCL GHPEEFYNLV RFRIGGKRKV MPKMDQDSLS SSLKTCYKYLNQTSRSFAAV IQALDGEMRN AVCIFYLVLR ALDTLEDDMT ISVEKKVPLL HNFHSFLYQP DWRFMESKEKDRQVLEDFPT ISLEFRNLAE KYQTVIADIC RRMGIGMAEFLDKHVTSEQE WDKYCHYVAGLVGIGLSRLF SASEFEDPLV GEDTERANSM GLFLQKTNII RDYLEDQQGG REFWPQEVWS RYVKKLGDFA KPENIDLAVQCLNELITNAL HHIPDVITYL SRLRNQ.

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