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Anti-CD40 Polyclonal Antibody

CAT: 0793-39-2037-100Size: 100 µg/VialDry Ice: NoHazardous: No
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CAT#:0793-39-2037-100Size:100 µg/Vial
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.
Product Name Alternative
Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD40; CD40; TNFRSF5
Gene Name
CD40
Gene ID
958
UniProt
P25942
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human CD40 (20-37aa, PEPPTACREKQYLINSQC) .
Target Antigen
Tumor necrosis factor receptor superfamily member 5
Clonality
Polyclonal
Applications
WB
Purification
Immunogen affinity purified.
Format
Lyophilized
Components
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.
Storage Conditions
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Applications Notes
Western blot : 0.1-0.5μg/ml
Isotype
Rabbit IgG

UniProtKB · P25942

Tumor necrosis factor receptor superfamily member 5

TNR5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P25942
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD40
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
E1P5S9, Q53GN5, Q5JY15, Q5U007, Q7M4Q8, Q86YK5, Q9BYU0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Biological process

Immunity

Molecular function

Receptor

Domain

RepeatSignalTransmembraneTransmembrane helix

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