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Polyclonal Antibody to WASP

CAT: 0793-35-1800-50Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0793-35-1800-50Size:50 μL
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Description
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
Product Name Alternative
THC|| THC1|| IMD2
Gene Name
WAS
Gene ID
7454
UniProt
P42768
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.
Target Antigen
WASP
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 53kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG

UniProtKB · P42768

Actin nucleation-promoting factor WAS

WASP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P42768
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WAS
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9BU11, Q9UNJ9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

CytoplasmCytoskeletonNucleus

Disease

Disease variant

PTM

Phosphoprotein

Domain

Repeat

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