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Polyclonal Antibody to TRPC6

CAT: 0793-35-1659-50Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0793-35-1659-50Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) .
Product Name Alternative
TRP6|| FSGS2|| FLJ11098
Gene Name
Trpc6
Gene ID
22068
UniProt
Q61143
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide Corresponding to the amino terminal sequence derived from mouse TRPC6.
Target Antigen
TRPC6
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 100kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG

UniProtKB · Q61143

Short transient receptor potential channel 6

TRPC6_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q61143
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Trpc6
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
TrpC6
EC number
—
Processing
—
Secondary accessions
B9EIW2, Q9Z2J1
Protein keywords

Technical term

3D-structureReference proteome

Domain

ANK repeatRepeatTransmembraneTransmembrane helix

Ligand

Calcium

Molecular function

Calcium channelIon channel

Biological process

Calcium transportIon transportTransport

Cellular component

Cell membraneMembrane

PTM

GlycoproteinPhosphoprotein

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Alternative Products

CatalogName
MBS8569792-01TRPC6 Polyclonal Antibody
APR13813GPolyclonal TRPC6 Antibody
HV333014-01Anti-TRPC6 Polyclonal Antibody
JOT-AP05270-01TRPC6 Rabbit Polyclonal Antibody
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