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Anti-Hu CD218a Purified

CAT: 0793-30-2815-0.1Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0793-30-2815-0.1Size:0.1 mg
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Description
CD218a, an approximately 62 kDa type I transmembrane glycoprotein, is the alpha subunit of IL-18 receptor heterodimer. It is expressed in various immune cells, including lymphocytes, NK cells, and myeloid cells, as well as in heart, lung, liver, gut and another tissues. IL-18 is a proinflammatory cytokine, that promotes both Th1 and Th2 immune responses, induces IFN-gamma production and activates NK cells.Specificity :The mouse monoclonal antibody H44 recognizes an extracellular epitope of CD218a, the alpha subunit of IL-18 receptor.
Product Name Alternative
Interleukin 18 receptor 1 IL18R1, IL-18 R1, IL18-RA
Gene Name
IL18R1
Gene ID
8809
UniProt
Q13478
Reactivity
Human
Immunogen
Human CD218a expressed on a transfected NK0 cell line
Target Antigen
CD218a
Clonality
Monoclonal
Clone
H44
Applications
WB, IHC, FACS, IP, IHC-Fr
Purification
Purified by protein-A affinity chromatography.
Format
Purified
Components
Concentration: 1 mg/mLStorage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/mL.

UniProtKB · Q13478

Interleukin-18 receptor 1

IL18R_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13478
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL18R1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-18R-1, IL-18R1
EC number
3.2.2.6
Processing
Precursor
Secondary accessions
B2R9Y5, Q52LC9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoprotein

Molecular function

HydrolaseReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Biological process

Inflammatory response

Cellular component

Membrane

Ligand

NAD

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