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Anti-Human CD231 APC (Clone : B2D)

CAT: 0793-30-2617-100Size: 100 TestsDry Ice: NoHazardous: No
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CAT#:0793-30-2617-100Size:100 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD231 (TALLA-1, T-ALL-asociated antigen 1), also known as tetraspanin 7, is a 150 kDa (under reducing conditions 32-45 kDa) transmembrane glycoprotein of tetraspanin family, expressed in T-type acute lymphoblastic leukemia, neuroblastoma, and neuronal tissue. Mutations of CD231 gene are associated with X-linked mental retardation, Huntington ́s chorea, and myotonic dystrophy. CD231 interacts with integrins and may have a role in the control of neurite outgrowth. Antibodies to CD231 are important for detection of T-ALL and are potential targets of its treatment.Specificity : The mouse monoclonal antibody B2D recognizes an extracellular epitope of CD231 (TALLA-1, tetraspanin 7), a transmembrane glycoprotein expressed in neuronal tissue and T-ALL.
Product Name Alternative
TSPAN7, TALLA-1, MXS1, MRX58, TM4SF2, tetraspanin 7
Gene Name
TSPAN7
Gene ID
7102
Reactivity
Human
Immunogen
Human T-ALL cell line THP-6
Target Antigen
CD231
Clonality
Monoclonal
Clone
B2D
Applications
FACS
Purification
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Components
Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Applications Notes
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Isotype
Mouse IgG1
Conjugate
APC

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