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Polyclonal Antibody to Cactin

CAT: 0793-11-3026-25Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0793-11-3026-25Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CACTIN is a conserved protein, discovered as a novel interactor of Drosophila IkappaB protein Cactus. It is highly conserved during evolution and plays a key role in early embryonic development. It is characterized as a negative regulator of many different developmental processes, but only found to play an immune role in humans. CACTIN localizes to nuclear speckles and colocalizes with known splicing proteins. It binds to a putative component of the spliceosome, major role for CACTIN in splicing.
Product Name Alternative
CACTIN||C19orf29
Gene Name
CACTIN
Gene ID
58509
UniProt
Q8WUQ7
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant Cactin protein (amino acids 320-521) was used as the immunogen for this antibody.
Target Antigen
Cactin
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4μg/mL
Isotype
Rabbit IgG

UniProtKB · Q8WUQ7

Splicing factor Cactin

CATIN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WUQ7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CACTIN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NNA9, A9UL12, O75229, Q7LE08, Q9BTA6, Q9Y5A4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

Coiled coil

Cellular component

CytoplasmNucleusSpliceosome

Molecular function

Developmental protein

Biological process

ImmunityInnate immunitymRNA processingmRNA splicing

PTM

Isopeptide bondPhosphoproteinUbl conjugation

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Alternative Products

CatalogName
BT-AP01092-01CACTIN Polyclonal Antibody
NBP1-70775Rabbit Polyclonal Cactin Antibody
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