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Polyclonal Antibody to UNC93B

CAT: 0793-11-3004-25Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0793-11-3004-25Size:25 µg
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Description
Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene. Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling also they helps in transportation of TLRs (basically TLR7 and TLR9) from endoplasmic reticulum to endolysosomes. Diseases associated with UNC93B1 include herpes simplex encephalitis 1, and herpes simplex encephalitis. It is expressed in plasmocytoid dendritic cells (at protein level), antigen-presenting cells (high) and at lower level in kidney.
Product Name Alternative
UNC93B1||UNC93||UNC93B
Gene Name
UNC93B1
Gene ID
81622
UniProt
Q9H1C4
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant UNC93B protein (amino acids 300-597) was used as the immunogen for this antibody.
Target Antigen
UNC93B
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 4-6 μg/mL
Isotype
Rabbit IgG

UniProtKB · Q9H1C4

Protein unc-93 homolog B1

UN93B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H1C4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
UNC93B1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Unc-93B1, hUNC93B1
EC number
—
Processing
—
Secondary accessions
O95764, Q569H6, Q710D4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityAntiviral defenseImmunityInnate immunity

Cellular component

Cytoplasmic vesicleEndoplasmic reticulumEndosomeLysosomeMembrane

PTM

GlycoproteinPhosphoprotein

Domain

TransmembraneTransmembrane helix

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