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Protonstatin-1

CAT: 0804-HY-W317853-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W317853-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Protonstatin-1 is a selective plasma membrane (PM) H+-ATPase inhibitor (IC50 of 3.9 μM) that inhibits auxin transport. Protonstatin-1 interacts with the PM H+-ATPase central loop and may thus impede the functions of the N- and/or P-domain to inhibit the pump activity[1][2].
CAS Number
521972-99-6
UNSPSC
12352005
Hazard Statement
H317, H319
Target
Proton Pump
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/protonstatin-1.html
Concentration
10mM
Purity
98.47
Solubility
DMSO : 70 mg/mL (ultrasonic)
Smiles
O=C1NC(S/C1=C\C2=CC=CO2)=S
Molecular Formula
C8H5NO2S2
Molecular Weight
211.26
Precautions
H317, H319
References & Citations
[1]Yongqing Yang, et al. Testing the polar auxin transport model with a selective plasma membrane H+ -ATPase inhibitor. J Integr Plant Biol. 2022 Jun;64 (6) :1229-1245.|[2]Yongqing Yang, et al. Screening of protonstatin-1 (PS-1) analogs for improved inhibitors of plant plasma membrane H+-ATPase activity. Front Plant Sci. 2022 Oct 12:13:973471.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported