Adenosine dialdehyde
CAT:
804-HY-123055-02
Size:
10 mM / 1 mL
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Adenosine dialdehyde
- CAS Number: 34240-05-6
- UNSPSC Description: Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM)[1]. Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research[1][2].
- Target Antigen: Nucleoside Antimetabolite/Analog
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/adenosine-dialdehyde.html
- Purity: 99.00
- Solubility: DMSO : 10 mg/mL (ultrasonic)
- Smiles: O=CC(OC(C=O)CO)N1C=NC2=C(N)N=CN=C12
- Molecular Weight: 265.23
- References & Citations: [1]G V Madhavan, et al. Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem|[2]B Bostrom, et al. Inhibitory effect of adenosine dialdehyde on in situ murine neuroblastoma growth.Cancer Res. 1988 Nov 1;48(21):5933-6.|[3]V Ramakrishnan, et al. Adenosine dialdehyde and neplanocin A: Potent inhibitors of S-adenosylhomocysteine hydrolase in neuroblastoma N2a cells. Neurochem Int. 1987;10(4):423-31.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported