TIMP1 Protein (Native, Rat)

• Abbreviation :

  TIMP1

• Synonyms :

  Timp, TIMP-1, Timp1

• Host :

  HEK 293

• Tag :

  Native

• Endotoxin :

  < 1.0 EU per μg of the protein as determined by the LAL method

• Purity :

  ≥ 97 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

• Bioactivity :

  Measured by its ability to inhibit human MMP2 cleavage of a fluorogenic peptide substrate MCA-PLGLDPA-AR-NH2, AnaSpec Catalog # 27076. The IC50 value is approximately 4 nM.

• Function :

  Met1-Ala217

• Molecular Weight :

  The recombinant rat TIMP1 consists of 194 amino acids and has a predicted molecular mass of 21.5 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 28 kDa in SDS-PAGE under reducing conditions.

• Species :

  Rat