TIMP1 Protein (Native, Human)

• Abbreviation :

  TIMP1

• Synonyms :

  CLGI, EPA, EPO, HCI, TIMP, TIMP-1

• Host :

  HEK 293

• Tag :

  Native

• Endotoxin :

  < 1.0 EU per μg of the protein as determined by the LAL method

• Purity :

  ≥ 97 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

• Bioactivity :

  Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate MCA-PLGL-DPA-AR-NH2 (R&D Systems, Catalog # ES001) . The IC50 value is < 6 nM.

• Function :

  Cys24-Ala207

• Molecular Weight :

  The recombinant human TIMP1 comprises 184 amino acids with a predicted molecular mass of 21 kDa. It migrates as an approximately 26 kDa band in SDS-PAGE under reducing conditions.

• Species :

  Human