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Beta-asarone

CAT: 0804-HY-N1501-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1501-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Beta-asarone is an orally active and BBB-penetrable anti-inflammatory agent and neuroprotective agent, which is the major ingredient of Acorus tatarinowii Schott. Beta-asarone can protect nerve cells from apoptosis and autophagy, inhibit expression of α-synuclein, as well as myocardial protection. Beta-asarone can be used in the study of neurological and cardiovascular diseases[1][2][3][4].
CAS Number
5273-86-9
UNSPSC
12352005
Hazard Statement
H302
Target
α-synuclein
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/beta-asarone.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C/C=C\C1=C(OC)C=C(OC)C(OC)=C1
Molecular Formula
C12H16O3
Molecular Weight
208.25
Precautions
H302
References & Citations
[1]Zhang QS, et al. Beta-asarone protects against MPTP-induced Parkinson's disease via regulating long non-coding RNA MALAT1 and inhibiting α-synuclein protein expression. Biomed Pharmacother. 2016 Oct;83:153-159.|[2]Xue Z, et al. Beta-asarone attenuates amyloid beta-induced autophagy via Akt/mTOR pathway in PC12 cells. Eur J Pharmacol. 2014 Oct 15;741:195-204.|[3]Liu J, et al. Beta-asarone attenuates neuronal apoptosis induced by Beta amyloid in rat hippocampus. Yakugaku Zasshi. 2010 May;130 (5) :737-46.|[4]Xiao B, et al. Beta-Asarone Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting Inflammatory Response and NLRP3 Inflammasome Mediated Pyroptosis. Biol Pharm Bull. 2020 Jul 1;43 (7) :1046-1051.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
α-synuclein

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