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BACE1 Protein (C-cleavage, Human)

CAT: 1543-P522302Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P522302Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Abbreviation
BACE1
Synonyms
ASP2, BACE, HSPC104, KIAA1149
Host
HEK 293
Tag
C-cleavage
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
Measured by its ability to cleave a fluorescent peptide substrate Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys (Dpn) -Arg-Arg-NH2 (Catalog# ES004, R&D Systems) . Cleavage of ES004 can be measured using excitation and emission wavelength of 320 and 405 nm, respectively. The specific activity is >3.5 pmoles/min/μg.
Function
Met1-Thr457
Molecular Weight
The recombinant human BACE1 consists of 442 amino acids and has a calculated molecular mass of 49 kDa. As a result of glycosylation, the rhBACE1 migrates as an approximately 65 kDa protein in SDS-PAGE under reducing conditions.
Species
Human

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