LDLR Protein (C-His, Human)

CAT: 1543-P512801Size: 100 µgDry Ice: NoHazardous: No

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CAT#:1543-P512801Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Abbreviation

LDLR

Synonyms

FH, FHC, LDL R, LDL Receptor, LDLCQ2, LDLR, Low-Density Lipoprotein Receptor

UniProt

P01130

Host

HEK 293

Tag

C-His

Applications

ELISA

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 85 % as determined by reducing SDS-PAGE.

Bioactivity

1. Immobilized human PCSK9 at 10 μg/ml (100 μl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 μg/ml. 2. Immobilized mouse PCSK9 at 10 μg/ml (100 μl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 μg/ml.

Function

Met 1-Arg 788

Molecular Weight

86.0 kDa

Species

Human

UniProtKB · P01130

Low-density lipoprotein receptor

LDLR_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P01130
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: LDLR
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: LDL receptor
EC number: —
Processing: Precursor
Secondary accessions: B4DII3, B4DJZ8, B4DR00, B4DTQ3, C0JYY8, H0YLU8, H0YNT7, Q53ZD9, Q59FQ1, Q9UDH7

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCoated pitEndosomeGolgi apparatusLDLLysosomeMembrane

Biological process

Cholesterol metabolismEndocytosisHost-virus interactionLipid metabolismLipid transportSteroid metabolismSterol metabolismTransport

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Host cell receptor for virus entryReceptor

Related Products

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Alternative Products

Catalog	Name
MBS1579385-01	Recombinant Human LDLR Protein, C-His