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TNF-alpha; TNFA Protein (Human)

CAT: 1543-P518860Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P518860Size:100 µg
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Abbreviation
TNF-alpha; TNFA
Synonyms
Cachectin, TNF, TNF-Alpha, TNF-a, TNFA, TNFSF2, Tumor Necrosis Factor, Tumor Necrosis Factor Ligand Superfamily Member 2
UniProt
P01375
Host
E. coli
Applications
Cell culture
Endotoxin
< 0.01 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Measured in a cytotoxicity assay using L‐929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 10-50 pg/ml.
Function
Val77-Leu233
Molecular Weight
17.5 kDa
Species
Human

UniProtKB · P01375

Tumor necrosis factor

TNFA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01375
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
O43647, Q9P1Q2, Q9UIV3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cell membraneMembraneSecreted

Molecular function

Cytokine

PTM

Disulfide bondGlycoproteinLipoproteinMyristatePhosphoprotein

Domain

Signal-anchorTransmembraneTransmembrane helix

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