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MMP-9 Protein (Human)

CAT: 1543-P517091Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P517091Size:100 µg
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Abbreviation
MMP-9
Synonyms
92 kDa gelatinase,92 kDa type IV collagenase, CLG4B, GELB, Gelatinase B, MANDP2, MMP9, Matrix metalloproteinase-9
UniProt
P14780
Host
HEK 293
Applications
Enzyme
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2, (AnaSpec, Cat#27076) . The specific activity is > 600 pmoles/min/μg. (Activation description: The proenzyme needs to be activated by APMA for an activated form)
Function
Met 1-Asp 707
Molecular Weight
76.3 kDa
Species
Human

UniProtKB · P14780

Matrix metalloproteinase-9

MMP9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P14780
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MMP9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MMP-9
EC number
3.4.24.35
Processing
Precursor
Secondary accessions
B2R7V9, Q3LR70, Q8N725, Q9H4Z1, Q9UCJ9, Q9UCL1, Q9UDK2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CalciumMetal-bindingZinc

Biological process

Collagen degradation

PTM

Disulfide bondGlycoproteinZymogen

Cellular component

Extracellular matrixSecreted

Molecular function

HydrolaseMetalloproteaseProtease

Domain

RepeatSignal