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PCSK9 Protein (C-Avi, Human)

CAT: 1543-P517421Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P517421Size:100 µg
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Abbreviation
PCSK9
Synonyms
NARC-1, NARC1, Neural Apoptosis-Regulated Convertase 1, PC9, PCSK9, Proprotein Convertase 9, Proprotein Convertase Subtilisin/Kexin Type 9, Subtilisin/Kexin-Like Protease PC9
UniProt
Q8NBP7
Host
HEK 293
Tag
C-Avi
Applications
ELISA
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Immobilized Human LDLR-His (Cat: PKSH033435) at 10μg/ml (100 μl/well) can bind Human PCSK9-BiotinylatedAVI. The ED50 of Human PCSK9-BiotinylatedAVI is 126.41ug/ml.
Function
Gln31-Gln692 (Val474Ile, Gly670Glu)
Molecular Weight
14&59 kDa
Species
Human
Conjugate
Biotinylated

UniProtKB · Q8NBP7

Proprotein convertase subtilisin/kexin type 9

PCSK9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NBP7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PCSK9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.-
Processing
Precursor
Secondary accessions
A8T640, C0JYY9, Q5PSM5, Q5SZQ2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisCholesterol metabolismLipid metabolismSteroid metabolismSterol metabolism

PTM

Autocatalytic cleavageDisulfide bondGlycoproteinPhosphoproteinSulfationZymogen

Ligand

Calcium

Cellular component

CytoplasmEndoplasmic reticulumEndosomeGolgi apparatusLysosomeSecreted

Disease

Disease variant

Molecular function

HydrolaseProteaseSerine protease

Domain

Signal