Pseudouridine (Standard)

Pseudouridine (Standard)

• CAS Number: 1445-07-4
• UNSPSC Description: Pseudouridine (Standard) is the analytical standard of Pseudouridine. This product is intended for research and analytical applications. Pseudouridine is an isomer of the nucleoside uridine, and the most abundant modified nucleoside in non-coding RNAs. Pseudouridine in rRNA and tRNA can fine-tune and stabilize the regional structure and help maintain their functions in mRNA decoding, ribosome assembly, processing and translation[1][2][3][4].
• Target Antigen: DNA/RNA Synthesis; Endogenous Metabolite; Nucleoside Antimetabolite/Analog
• Type: Reference Standards
• Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/pseudouridine-standard.html
• Smiles: O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CNC2=O)O[C@@H]1CO
• Molecular Weight: 244.20
• References & Citations: [1]Carlile TM, et al. Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells. Nature. 2014 Nov 6;515(7525):143-6.|[2]M Charette, et al. Pseudouridine in RNA: what, where, how, and why. IUBMB Life. 2000 May;49(5):341-51.|[3]Junhui Ge, et al. RNA pseudouridylation: new insights into an old modification. Trends Biochem Sci. 2013 Apr;38(4):210-8.|[4]Anne C Rintala-Dempsey, et al. Eukaryotic stand-alone pseudouridine synthases - RNA modifying enzymes and emerging regulators of gene expression? RNA Biol. 2017 Sep 2;14(9):1185-1196.
• Shipping Conditions: Room temperature