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Eukaryotic Integrin Alpha M (CD11b)

CAT: 0338-TRV-043672-02Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-043672-02Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
ITGaM; ITG-AM; CR3A; MAC-1; MAC1A; MO1A; Complement Component 3 Receptor 3 Subunit; Cell surface glycoprotein MAC-1 subunit alpha; Neutrophil adherence receptor
UniProt
P11215
Expression System
Eukaryotic expression
Tag
N-terminal His Tag and C-terminal Fc Region of Human IgG1
Source
Eukaryotic expression
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
Field of Research
CD & Adhesion molecule; Tumor immunity; Infection immunity; Immune molecule
Endotoxin
<1.0EU per 1μg (determined by the LAL method)
Purity
> 80%
Form
Freeze-dried powder
Buffer
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Calculated Molecular Weight
44.78kDa
Observed Molecular Weight
60kDa
Fragment
Ala850~Val975
Isoelectric Point
8.5
Subcellular Location
Membrane
Product Name Synonym
Integrin Alpha M
Host or Source
293F
Organism Species
Homo sapiens (Human)

UniProtKB · P11215

Integrin alpha-M

ITAM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11215
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGAM
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q4VAK0, Q4VAK1, Q4VAK2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMagnesiumMetal-binding

Biological process

Cell adhesionImmunityInnate immunity

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

IntegrinReceptor

Domain

RepeatSignalTransmembraneTransmembrane helix

Disease

Systemic lupus erythematosus

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