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Odronextamab Biosimilar - Research Grade

CAT: 1148-ICH5027-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:1148-ICH5027-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ichorbio’s Odronextamab biosimilar is a hinge-stabilized, fully human IgG4-based CD3 x CD20 bispecific antibody (bsAb) that has demonstrated encouraging safety, tolerability and preliminary efficacy in a first-in-human study of patients with relapsed/refractory B-cell non-Hodgkin lymphoma.
Product Name Alternative
REGN 1979
Reactivity
Human
Target
CD3 + CD20
Isotype
IgG4
Sequence
https://www.imgt.org/mAb-DB/
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Specificity
Detects human CD3/CD20. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Odronextamab.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control
Bulk Human IgG4 Isotype Control (IB4) [ICH2257]

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