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Human ErbB2/Her2 Recombinant Protein

CAT: 0519-PROTP04626-100ugSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0519-PROTP04626-100ugSize:100 µg
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Description
Human ErbB2/Her2 Recombinant Protein expressed in Baculovirus with His-tag. Sequence domain: 23-652aa. Application (s) : SDS-PAGE. Endotoxin: < 1 EU per 1ug of protein (determined by LAL method) .
Synonyms
Receptor tyrosine-protein kinase erbB-2 isoform, ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Gene Name
ERBB2
UniProt
P04626
Tag
His-Tag
Source
Baculovirus
Applications
SDS-PAGE
Field of Research
Cancer
Purification
> 85% by SDS-PAGE
Concentration
0.25mg/mL (determined by Bradford assay)
Form
Liquid
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long-term storage, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. (Ships with gel ice.)
Observed Molecular Weight
70.4 kDa (638aa)
Contents
Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

UniProtKB · P04626

Receptor tyrosine-protein kinase erbB-2

ERBB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04626
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ERBB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
B2RZG3, B4DHN3, Q14256, Q6LDV1, Q9UMK4, X5D2V5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorKinaseReceptorTransferaseTyrosine-protein kinase

Coding sequence diversity

Alternative initiationAlternative splicingChromosomal rearrangement

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCell projectionCytoplasmEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

SignalTransmembraneTransmembrane helix

Biological process

TranscriptionTranscription regulation

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