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Anti-CBLL1 Antibody

CAT: 0519-A09377-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A09377-1Size:100 µL
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Background
Cbl proto‐oncogene E3 ubiquitin protein ligase‐like 1, RNF188, Hakai (CBLL1) is an evolutionarily conserved E3 ubiquitin ligase containing a RING‐finger domain. CBLL1 contains a typical RING‐finger, short pTyr‐binding domain, and proline‐rich domain. CBLL1 expression is upregulated in human colon and gastric cancer tissues, and CBLL1 has been reported to induce anchorage‐dependent cell growth. CBLL1 immunostaining was observed in both the nuclei and cytoplasm of cancer cells. (PMID: 31124298, PMID: 31646569, PMID: 21191016)
Description
Boster Bio Anti-CBLL1 Antibody catalog # A09377-1. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse.
Synonyms
HAKAI; EC:2.3.2.27; E3 ubiquitin-protein ligase Hakai; c-Cbl-like protein 1; Casitas B-lineage lymphoma-transforming sequence-like protein 1
Gene Name
CBLL1
UniProt
Q75N03
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E.coli-derived human CBLL1 recombinant protein (Position: N3-H225) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Cbl proto-oncogene like 1
Protein Name
E3 ubiquitin-protein ligase Hakai
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

UniProtKB · Q75N03

E3 ubiquitin-protein ligase Hakai

HAKAI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q75N03
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CBLL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
B7ZM03, Q8TAJ4, Q9H5S6
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

Developmental proteinTransferase

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Biological process

Ubl conjugation pathway

Domain

Zinc-finger

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