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Anti-Emp (E207) MAEA Antibody

CAT: 0519-A08766Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A08766Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-Emp (E207) MAEA Antibody catalog # A08766. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Macrophage erythroblast attacher; Cell proliferation-inducing gene 5 protein; Erythroblast macrophage protein; Human lung cancer oncogene 10 protein; HLC-10; MAEA; EMP; HLC10, PIG5
Gene Name
MAEA
UniProt
Q7L5Y9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 178-228 of Human Emp.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
45287 MW
Applications Notes
IHC: 1:50-1:200
Gene Name Synonym
Macrophage erythroblast attacher
Subcellular Location
Nucleus matrix
Protein Name
Macrophage erythroblast attacher
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

UniProtKB · Q7L5Y9

E3 ubiquitin-protein transferase MAEA

MAEA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q7L5Y9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAEA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
O95285, Q5JB54, Q6ZRD6, Q9BQ11, Q9H9V6, Q9H9Z4, Q9NW84
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Actin-bindingTransferase

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionErythrocyte maturationUbl conjugation pathway

Cellular component

Cell membraneCytoplasmCytoskeletonMembraneNucleus

Ligand

Metal-bindingZinc

PTM

PhosphoproteinUbl conjugation

Domain

Zinc-finger

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