Anti-FBXO7 Antibody

• Description :

  Boster Bio Anti-FBXO7 Antibody catalog # A04086. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms :

  F-box only protein 7; FBXO7; FBX7

• Gene Name :

  FBXO7

• UniProt :

  Q9Y3I1

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthetic peptide from human protein at AA range: 371-420

• Applications :

  WB, ELISA

• Purification :

  Immunogen affinity purified

• Concentration :

  1 mg/mL

• Form :

  Liquid

• Function :

  Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination. .

• Storage Conditions :

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  58503 MW

• Gene Name Synonym :

  F-box only protein 7

• Subcellular Location :

  Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytosol. Predominantly cytoplasmic. A minor proportion is detected in the nucleus. Relocates from the cytosol to depolarized mitochondria.

• Contents :

  PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.