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Anti-WARS Antibody

CAT: 0519-A02444Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A02444Size:100 µL
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Description
Boster Bio Anti-WARS Antibody catalog # A02444. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Tryptophan--tRNA ligase, cytoplasmic;6.1.1.2
Gene Name
WARS
UniProt
P23381
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human Tryptophanyl-tRNA synthetase 1 (NP_776049.1) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
53165 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Tryptophan--tRNA ligase, cytoplasmic
Subcellular Location
Cytoplasm.
Protein Name
Tryptophan--tRNA ligase, cytoplasmic
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

UniProtKB · P23381

Tryptophan--tRNA ligase, cytoplasmic

SYWC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P23381
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WARS1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
6.1.1.2
Processing
—
Secondary accessions
A6NGN1, A6NID3, P78535, Q502Y0, Q53XB6, Q9UDI5, Q9UDL3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Aminoacyl-tRNA synthetaseLigase

Biological process

AngiogenesisProtein biosynthesis

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cytoplasm

Disease

Intellectual disabilityNeurodegenerationNeuropathy

PTM

Phosphoprotein

Related Products

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PROTP23381-20ugHuman WARS Recombinant Protein
PROTP23381-01Human WARS Recombinant Protein
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A12130-1Anti-WARS2 Antibody
LS007453Tryptophanyl tRNA synthetase (WARS) (NM_004184) Human Over-expression Lysate
A12130Anti-SYWM WARS2 Antibody
LS007453-20ugTryptophanyl tRNA synthetase (WARS) (NM_004184) Human Over-expression Lysate
LS007453-100ugTryptophanyl tRNA synthetase (WARS) (NM_004184) Human Over-expression Lysate
A02444-2Anti-WRS/WARS1 Antibody Picoband®

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