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Anti-JUN Antibody (C-term)

CAT: 0519-A02038-400ulSize: 400 µLDry Ice: NoHazardous: No
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CAT#:0519-A02038-400ulSize:400 µL
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Background
JUN is the putative transforming gene of avian sarcoma virus 17. JUN is a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Description
Boster Bio Anti-JUN Antibody (C-term) (Catalog # A02038) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.
Synonyms
Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN
Gene Name
JUN
UniProt
P05412
Host
Rabbit
Reactivity
Human
Immunogen
This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the C-terminal region of human JUN.
Clonality
Polyclonal
Tissue Specificity
Expressed in the developing and adult prostate and prostate cancer cells.
Applications
WB, IHC-P, Flow Cytometry
Field of Research
Cancer, Immunology, Signal Transduction, Anti-Wnt-Pathway (plus Lgr5) Antibodies, TLR Signaling, T Cells, Inflammation, Apoptosis
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
109957482208395212618758172106462462330624623306
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
35676 Da
Subcellular Location
Nucleus.
Prediction Reactivity
Bovine, Chicken, Mouse, Pig, Rat
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

UniProtKB · P05412

Transcription factor Jun

JUN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05412
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
JUN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6FHM7, Q96G93
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Cellular component

Nucleus

Disease

Proto-oncogene

Biological process

TranscriptionTranscription regulation

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