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Anti-Elastin/ELN Antibody

CAT: 0519-A01300-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A01300-1Size:100 µL
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Background
Elastic fibers are an abundant and integral part of many extracellular matrices, in which they provide the elastic properties to tissues such as arterial, lung, and skin. Elastic fibers are consisting of an elastin core surrounded by a mantle of fibrillin-rich microfibrils (PMID: 12082143) . Elastin is an extremely durable, insoluble biopolymer formed through the lysine-mediated crosslinking of its soluble precursor tropoelastin, which is an approximately 60-70 kDa protein (PMID: 15837523) . Deletions and mutations in the elastin gene (ELN) are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa.
Description
Boster Bio Anti-Elastin/ELN Antibody catalog # A01300-1. Tested in WB, IHC, IP, ELISA applications. This antibody reacts with Human.
Synonyms
ELN; WS; WBS; Tropoelastin; SVAS
Gene Name
ELN
UniProt
P15502
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human Elastin/ELN recombinant protein (Position: V309-K656) .
Clonality
Polyclonal
Applications
WB, IHC, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Elastin
Protein Name
Elastin
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

UniProtKB · P15502

Elastin

ELN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15502
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ELN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B3KTS6, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5
Protein keywords

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondHydroxylation

Cellular component

Extracellular matrixSecreted

Technical term

Proteomics identificationReference proteome

Domain

RepeatSignal

Disease

Williams-Beuren syndrome

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