Products for Research Use Only
RegisterLogin

Rb Polyclonal Antibody

CAT: 0749-ABP0117Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP0117Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
RB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Description
Rabbit Anti-Rb Polyclonal Antibody
Product Name Alternative
RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
Gene ID
5925
Accession Number
P06400
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human Rb around the non-phosphorylation site of S780
Clonality
Polyclonal
Tag
Retinoblastoma-associated protein
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
106kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Rb Polyclonal Antibody detects endogenous levels of Rb protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P06400
Isotype
Rabbit IgG

Related Products

CatalogName
ABP55998-01Rb (phospho Ser612) Polyclonal Antibody
ABP56000-01Rb (phospho Thr821) Polyclonal Antibody
ABP55999-01Rb (phospho Ser788) Polyclonal Antibody
ABP55996-01Rb (phospho Thr826) Polyclonal Antibody
ABP56001-01Rb (phospho Ser249) Polyclonal Antibody
ABP55995-01Rb (phospho Ser811) Polyclonal Antibody
ABP0044Rb (phospho Ser780) Polyclonal Antibody
ABP55994-01Rb (phospho Ser795) Polyclonal Antibody
ABP50402-01Rb (phospho Ser807) Polyclonal Antibody
ABP55997-01Rb (phospho Ser608) Polyclonal Antibody

Alternative Products

CatalogName
APR12525GPolyclonal MeCP2 polyclonal antibody
APR00376GPolyclonal BMI1 polyclonal antibody
APR00459GPolyclonal CHD4 polyclonal antibody
APR00451GPolyclonal SPI1 polyclonal antibody
APR00373GPolyclonal EzH2 polyclonal antibody
APR14018GPolyclonal YY1 polyclonal antibody
PTX18700-100UCN3 Polyclonal Polyclonal Antibody
PTX18688-100TKT Polyclonal Polyclonal Antibody
PTX18684-100TGFA Polyclonal Polyclonal Antibody
PTX18678-100SYT1 Polyclonal Polyclonal Antibody

Popular Products