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Rabbit Polyclonal Antibody to CERS4

CAT: 1725-P42939-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P42939-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
Product Name Alternative
Trh1; LASS4
Swiss Prot
Q9HA82
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human ceramide synthase 4
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
CERS4
Bands Size
46kDa