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Rabbit Polyclonal Antibody to ELF4

CAT: 1725-P42694-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P42694-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter By similarity. Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 By similarity. Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway. UniProtKB Q9Z2U4Miyazaki Y., Oncogene 13:1721-1729 (1996) .Aryee D.N.T., Gene 210:71-78 (1998) .Ross M.T., Nature 434:325-337 (2005) .
Product Name Alternative
E74-like factor 4; E74-like factor 4 (ets domain transcription factor) ; ELFR; ETS-related transcription factor Elf-4; Mef
Swiss Prot
Q99607
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from internal of human ELF4.
Clonality
Polyclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
ELF4
Bands Size
70kDa

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