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Rabbit Polyclonal Antibody to PARD3

CAT: 1725-P42064-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P42064-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions By similarity. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.Joberty G., Nat. Cell Biol. 2:531-539 (2000) .Fang C.M., Cell Res. 11:223-229 (2001) .Kohjima M., Biochem. Biophys. Res. Commun. 299:641-646 (2002) .
Product Name Alternative
Partitioning-defective 3 homolog; PARD-3; PAR-3; Atypical PKC isotype-specific-interacting protein; ASIP
Swiss Prot
Q8TEW0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from internal of human PARD3.
Clonality
Polyclonal
Applications
WB, IF
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
PARD3
Bands Size
151kDa

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