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Rabbit Polyclonal Antibody to IRF2

CAT: 1725-P41910-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P41910-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS) ) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.Itoh S., Nucleic Acids Res. 17:8372-8372 (1989) .Cha Y., J. Biol. Chem. 269:5279-5287 (1994) .Staal A., J. Cell. Physiol. 185:269-279 (2000) .
Product Name Alternative
IRF2; Interferon regulatory factor 2
Swiss Prot
P14316
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from internal of human IRF2.
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
IRF2
Bands Size
47kDa

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