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Rabbit Polyclonal Antibody to AKAP1

CAT: 1725-P41868-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P41868-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase By similarity.Wang L., Proc. Natl. Acad. Sci. U.S.A. 98:3220-3225 (2001) .Chatterjee T.K., Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.The MGC Project Team, Genome Res. 14:2121-2127 (2004) .
Product Name Alternative
A kinase anchor protein 10; mitochondrial [Precursor]; Protein kinase A-anchoring protein 10; PRKA10; Dual specificity A kinase-anchoring protein 2
Swiss Prot
O43572
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from Internal of human AKAP10.
Clonality
Polyclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
AKAP1
Bands Size
73kDa

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