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Rabbit Polyclonal Antibody to eIF2B (Ab-67)

CAT: 1725-P41787-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P41787-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.Pathak V.K., Cell 54:633-639 (1988) .Deloukas P., Nature 414:865-871 (2001) .Olsen J.V., Cell 127:635-648 (2006) .
Product Name Alternative
DKFZp686L18198; eIF-2-beta; EIF2; EIF2B; EIF2beta
Swiss Prot
P20042
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from N-terminal of human eIF2B.
Clonality
Polyclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
EIF2B (Ab-67)
Bands Size
40kDa

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