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Rabbit Polyclonal Antibody to MAP2K4

CAT: 1725-P41529-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P41529-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SAPK/Erk kinase (SEK1), also known as MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflamatory cytokines (1-3) . Activation of SEK1 occurs through MEKK phosphorylation of serine and threonine residues at positions 257 and 261, respectively. Like MEK, SEK is a dual-specificity protein kinase that phosphorylates SAPK/JNK at a conserved T*PY* site in its activation loop (4) . Phosphorylation by Akt at Ser80 inhibits SEK1 and suppresses stress-activated signal transduction (5) .
Product Name Alternative
JNKK1; MEK4; MKK4; PRKMK4; SERK1
Swiss Prot
P45985
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.352~356 (E-S-K-R-P) derived from Human MAP2K4.
Clonality
Polyclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
MAP2K4
Bands Size
44kDa