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Rabbit Polyclonal Antibody to Dnmt3b

CAT: 1725-P33133-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P33133-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3b is a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome.
Product Name Alternative
DNA (cytosine-5) -methyltransferase 3B, Dnmt3b, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, MHsaIIIB, DNMT3B
Swiss Prot
Q9UBC3
Host
Rabbit
Reactivity
Human
Immunogen
This Dnmt3b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-417 amino acids from human Dnmt3b.
Clonality
Polyclonal
Applications
WB, IHC-P
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) .
Antibody Type
Primary antibody
Protein Name
Dnmt3b
Bands Size
95.8kDa

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