Products for Research Use Only
RegisterLogin

Ilunocitinib

CAT: 0804-HY-132819-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-132819-02Size:10 mM - 1 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ilunocitinib (compound 27) is a JAK inhibitor (extracted from patent WO2009114512A1) [1].
CAS Number
1187594-14-4
Product Name Alternative
LY-3411067
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ilunocitinib.html
Purity
98.24
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
N#CCC1(CN(S(=O)(C2CC2)=O)C1)N3N=CC(C4=C5C=CNC5=NC=N4)=C3
Molecular Formula
C17H17N7O2S
Molecular Weight
383.43
References & Citations
[1]James D. Rodgers, et al. Azetidine and cyclobutane derivatives as jak inhibitors. Patent. WO2009114512A1.|[2]Forster S, et al. Comparative efficacy and safety of ilunocitinib and oclacitinib for the control of pruritus and associated skin lesions in dogs with atopic dermatitis. Vet Dermatol. 2025 Jan 6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Ilunocitinib
CAS Number1187594-14-4
PubChem CID44231134
IUPAC Name2-[1-cyclopropylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile
Molecular FormulaC17H17N7O2S
Molecular Weight383.4
XLogP-0.3
Topological Polar Surface Area129
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count27
Formal Charge0
Complexity734
SMILES
C1CC1S(=O)(=O)N2CC(C2)(CC#N)N3C=C(C=N3)C4=C5C=CNC5=NC=N4
InChI
InChI=1S/C17H17N7O2S/c18-5-4-17(9-23(10-17)27(25,26)13-1-2-13)24-8-12(7-22-24)15-14-3-6-19-16(14)21-11-20-15/h3,6-8,11,13H,1-2,4,9-10H2,(H,19,20,21)
InChIKey
RVOUEXFKIYNODQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Ilunocitinib
CAS: 1187594-14-4
CID: 44231134
Formula: C17H17N7O2S
MW: 383.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight383.4
XLogP3-0.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass383.11644398
Monoisotopic Mass383.11644398
Topological Polar Surface Area129 Ų
Heavy Atom Count27
Formal Charge0
Complexity734
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA4915-25Ilunocitinib

Popular Products