Benzohydroxamic acid

• Description :

  Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with significant antifungal activity. The Ki values of BHA against the CDAs of Verticillium dahliae and Puccinia striiformis f. sp. tritici are 8.31 μM and 9.83 μM, respectively. Benzohydroxamic acid can restore the defense responses of infected host plants, upregulate the expression of defense-related genes, and reduce the growth and reproduction of fungi in plants. Benzohydroxamic acid can be used in the research of the field of controlling agricultural fungal diseases, such as various plant fungal diseases caused by Verticillium dahliae, Puccinia striiformis and other fungi, like cotton wilt and wheat stripe rust [1].

• Product Name Alternative :

  BHA

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Fungal

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Purity :

  99.99

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(NO)C1=CC=CC=C1

• Molecular Formula :

  C7H7NO2

• Molecular Weight :

  137.14

• Precautions :

  H315, H319

• References & Citations :

  [1]Liu L, et al. Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun. 2023 Jun 29;14 (1) :3857.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound2

• Clinical Information :

  Phase 3

• CAS Number :

  [495-18-1]